Engineering living medicines
We program cells to sense, respond, and treat disease—advancing a new era of living therapies
for Human Health
Our lab approaches biology as an engineering discipline—one in which living systems can be measured, modeled, programmed, and redesigned for human health. We combine synthetic and systems biology with broader quantitative, computational, and bioengineering tools to understand how cells sense and respond to their environments and use those insights to design programmable cells, diagnostics, and therapeutics.
Microbial Medicines
Engineered bacteria that selectively colonize tumors and deliver therapeutic payloads.
Synthetic Biology
Programmable genetic circuits that allow cells to sense, compute, and respond.
Cooperative Therapies
Bacteria working with immune cells, viruses, nanoparticles, and other therapeutic modalities.
Biological Dynamics
Computational and artificial intelligence approaches reveal biological dynamics from microscopy and sequencing data at the single-cell level.